The CFA has been active both locally and nationally in representing the interests of persons living with HIV/AIDS, especially the affected population in Houston. The CFA's staff has attended numerous national and international conferences, participated in meetings sponsored by the National Institutes of Health and the Food and Drug Administration, and played an advocacy role with pharmaceutical companies that conduct research on HIV/AIDS. The CFA's executive director, Paul Simmons, serves as co-chair of the Community Science Committee of the AIDS Clinical Trials Group (ACTG). Over the years, the ACTG's work has defined the clinical management of HIV infection.

The CFA is committed to keeping Houston a vibrant hub of both scientific and clinical research into HIV, to advancing HIV vaccinology in Houston, to educating the community on the treatment of HIV infection and it complications, and to supporting novel approaches that reduce community viral load and thus the potential for HIV transmission.

As always, The CFA's staff recognize the importance of research in the search for a cure for AIDS, and of Houston's role in that search.